Swine have proven to be particularly effective in biomedical research because of their genetic makeup, which closely resembles that of humans.

This fact has enabled swine-based research to achieve more relevant and significant findings than research using other animals such as rats or rabbits.

The importance of this medical research is substantial, given the medical applications for human knowledge and advancement. Ultimately, it can help us have a better understanding of our own biological functions, needs and treatments.

Swine have been used in biomedical research in a variety of areas: cardiovascular, gastrointestinal, metabolic, liver, reproductive and infectious disease. They have also helped researchers learn more about drug addiction and wound healing.

Midwest Research Swine has provided High Health Status swine for research studies in arteriosclerosis, heart transplants, bioprosthesis heart valves, intestinal transplants, diabetes and pancreatic transplants, liver transplants, uterine cell physiology, bronchial and tracheal stent, renal transplants, immune and antibiotic and vaccine trials.

Research Applications

Cardiovascular cardiac arrhythmias myofibrillar degeneration   *myocardial infarct persistent ductus arteriosus cardioplagia growing heart model   *arteriosclerosis cardiomyopathy endocarditis   *heart transplant   *bioprosthesis heart valve   *aortic grafts   *pacemaker development Gastrointestinal peptic ulcers   *intestinal transplant granulomatous enteritis (Crohn’s) total parenteral nutrition Ileal bypass pneumatosis intestinalis gastric dilatation   *vascular shunts Metabolic   *diabetes and pancreatic transplant GM2 gangliosidosis bialbuminemia obesity malignant hyperthermia Liver   *Liver transplantation Reproductive surgical techniques of organs and fetal cryptorchidism sex reversed xx males   *uterine cell physiology Neonatology neonatal necrotizing enterocolitis erythroblastosis iron deficiency anemia gross congenital abnormalities transient hypogamma- globulinemia of infancy

Pulmonary chronic bronchitis   *bronchial and tracheal stent Renal embryonal nephroma viral glomerulitis hypertension   *transplantation Immune Von Willebrand’s malignant lymphoma anaphylaxis Pityriasis Rosea Rheumatoid arthritis   *Immune alteration to toxicities Miscellaneous   *drug addiction heterochromia irides melanoma osteoporosis   *wound healing burn healing   *medical devices Infectious Disease   *tuberculosis   *vaccine trials   *antibiotic trials   *swine infectious disease

  *Asterisks indicate studies involving Midwest Research Swine’s pigs.